• Calanus finmarchicus as a novel source of health-promoting bioactive peptides: Enzymatic protein hydrolysis, characterization, and in vitro bioactivity 

      Matic, Josipa; Bøgwald, Isak; Tengstrand, Erik; Rønning, Sissel Beate; Afseth, Nils Kristian; Wubshet, Sileshi Gizachew (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-21)
      Calanus finmarchicus is a crustacean currently used as a source of marine lipid. The lipids are extracted by enzymatic protein hydrolysis, while the remaining peptide fraction is regarded as a byproduct. In the present work, ten different commercial proteases and endogenous C. finmarchicus proteases were used to produce a set of 63 protein hydrolysates. Protease concentration and hydrolysis time ...
    • Optical investigation of osteoarthritic human cartilage (ICRS grade) by confocal Raman spectroscopy: a pilot study 

      Kumar, Rajesh; Grønhaug, Kirsten Marie; Afseth, Nils Kristian; Isaksen, Vidar; Davies, Catharina de Lange; Drogset, Jon Olav; Lilledahl, Magnus Borstad (Journal article; Tidsskriftartikkel; Peer reviewed, 2015)
      Biomolecular changes in the cartilage matrix during the early stage of osteoarthritis may be detected by Raman spectroscopy. The objective of this investigation was to determine vibrational spectral differences among different grades (grades I, II, and III) of osteoarthritis in human osteoarthritic cartilage, which was classified according to the International Cartilage Repair Society (ICRS) grading ...